Aplenzin: Side Effects, Overdose and Pregnancy Information

Main ingredient in Aplenzin is Bupropion. Aplenzin, a fairly new antidepressant medication, is used to treat severe depression when all other drugs have been ineffective, primarily because of high risk of seizures. Aplenzin is also given to stop smoking habit. Aplenzin takes about 2-4 weeks to function properly.

APLENZIN SIDE EFFECTS

Common side effects of Aplenzin may include upset stomach, agitation, anxiety, dizziness, constipation, dry mouth, headache, appetite loss, nausea, vomiting, excessive sweating, rash, insomnia, and tremor. Rare side effects of Aplenzin may include severe allergic reactions, breathing difficulty, chest pain, impotence, urinary problems, confusion, sedation, fatigue, fever, euphoria, menstrual complaints, chills, delusions, suicidal thoughts, and weight gain or loss.

APLENZIN CAUTION

Those who have had seizures in the past, head injury or were diagnosed with eating disorders should discuss this with their physician before using Aplenzin.

If you have had any kind of heart, or liver or kidney disease, be sure to discuss this with your physician before starting Aplenzin. A lower dose may be needed.

About 25 percent of people who take Aplenzin experience appetite loss and weight loss of about 5 lbs or more.
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Do not take Aplenzin within the past two weeks of taking a monoamine oxidase inhibitor (MAO inhibitor) drug. This could result in a sudden and unsafe rise in blood pressure.

APLENZIN INTERACTIONS

Avoid alcohol while taking Aplenzin; an interaction between them may enhance the possibility of a seizure.

Check with your doctor before combining Aplenzin with the following:
Beta-blockers
Blood thinning drugs
Carbamazepine
Cimetidine
Cyclophosphamide
Levodopa
Major tranquilizers
MAO inhibitors
Nicotine patches
Orphenadrine
Other antidepressants
Phenobarbital
Phenytoin
Steroids
Theophylline

APLENZIN AND PREGNANCY

If you are or planning to become pregnant, inform your physician right away. The safety of taking Aplenzin during pregnancy is not well established.

Nursing mothers should switch to bottle-feed while taking Aplenzin.

APLENZIN DOSES

CHILDREN
Not recommended for children under 18.
ADULTS
Depression:
100-450 mg/day; divided into 3-4 doses. Not to exceed 450 mg in a 24-hour period.
Smoking Cessation
150 mg twice daily. Not to exceed 300 mg in a 24-hour period.

APLENZIN OVERDOSE

Symptoms of Aplenzin overdose may include hallucinations, loss of consciousness, seizures, angina, nausea, vomiting and breathing problems. If you suspect Aplenzin overdose, seek medical help right away.

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