Clomicalm: Veterinary Drug

Clomicalm is a veterinary medicine containing the active substance clomipramine. Clomicalm is available as tablets containing 5 mg, 20 mg or 80 mg clomipramine. Clomicalm is used as an aid in the treatment of dogs that have behavioural problems when separated from their owners, their normal home, or other dogs. These behavioural problems might be expressed for example by destructive behaviour or inappropriate defecation or urination in the house. Clomicalm should not be used on its own but only in dogs that are also undergoing behavioural therapy.

Clomicalm tablets are given twice a day. The strength and number of tablet(s) to use is adjusted according to the dog’s weight, so that the dog is given between 2 mg and 4 mg clomipramine per kg of the dog’s bodyweight per day.

CLOMICALM SIDE EFFECTS

Clomicalm may very rarely cause vomiting, changes in appetite, lethargy (sleepiness) or an elevation in liver enzymes, which are reversible when the product is discontinued. Effects on the liver have been reported, especially in dogs with existing liver problems. Vomiting may be reduced by giving the tablets with a small quantity of food.

At overdose with 20 mg/kg Clomicalm (5 times the maximum therapeutic dose), a reduction in heart rate were observed approximately 12 hours after dosing. Since Clomicalm has not been tested in pregnant or lactating bitches, its use is not recommended during pregnancy and lactation. Due to potential interactions, the administration of Clomicalm is not recommended in combination with a number of other medicines listed in the package leaflet.

CLOMICALM: PRECAUTIONS FOR HUMANS

Since accidental ingestion might cause serious reactions in children, the tablets are supplied in a bottle fitted with a child resistant closure.

This veterinary medicine has been developed especially for dogs and is not for use in humans. If a person accidentally takes the medicine, seek medical advice immediately and show the package leaflet or the label to a doctor.

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