Cordilox MR: Side Effects, Overdose and Pregnancy Information
Main ingredient in Cordilox MR is Verapamil. Cordilox MR is a type of drug known as a calcium channel blocker. This type of drug acts on the heart and blood vessels. Cordilox MR is used for Angina (chest pain) and Hypertension (high blood pressure).
Cordilox MR works by slowing down the movement of calcium through muscle cells by blocking 'calcium channels' on these muscle cells causing them to relax. By doing so Cordilox MR slows down the rate at which the heart beats and widens the blood vessels in the body.
Angina (chest pain) is caused by insufficient oxygen supply to the heart. Cordilox MR improves this oxygen supply and also reduces the effort the heart has to make to pump blood consequently reducing blood pressure.
CORDILOX MR SIDE EFFECTS
Side effects of Cordilox MR may include constipation,
flushing,
headache,
nausea, vomiting,
dizziness,
fatigue,
ankle swelling,
needles sensations,
slowed heart rate,
low blood pressure,
heart failure,
impaired liver function,
reversible enlargement of the gums, and
reversible enlargement of the breasts has been seen in elderly men under long-term treatment.
Cordilox MR Warning and Caution
Avoid drinking grapefruit juice while taking Cordilox MR, as it may increase the level of this drug in your blood.
Cordilox MR may affect your ability to drive a vehicle or operate machinery.
Cordilox MR may slow the breakdown of alcohol in the body. Therefore it could increase the level of alcohol in your blood and its effect.
Cordilox MR should be used with caution in people with decreased liver or kidney function, and heart failures.
Cordilox MR should not to be used in heart attack complicated by a slowed heart rate, heart failure or very low blood pressure, sick sinus syndrome,
uncontrolled heart failure,
slow heart rate of less than 50 beats per minute,
low blood pressure of less than 90mmHg systolic,
and porphyries.
Cordilox MR is not recommended for children.
Cordilox MR and Pregnancy
Cordilox MR should not be used during pregnancy. Seek medical advice from your physician if you get pregnant or plan to get pregnant while using Cordilox MR.
Cordilox MR passes into breast milk. Nursing mothers should switch to bottle-feed while taking Cordilox MR.
Cordilox MR Interaction
If Cordilox MR is used in combination with other medicines that lower blood pressure, this could cause the blood pressure to drop dangerously low.
Other drugs that reduce blood pressure include the following:
ACE inhibitors
Alpha-blockers
Alprostadil
Angiotensin II receptor antagonists
Antipsychotics
Baclofen
Benzodiazepines
Beta-blockers
Other calcium channel blockers
Clonidine
Diazoxide
Diuretics
Dopamine agonists
Hydralazine
Levodopa
MAOI antidepressants
Methyldopa
Minoxidil
Moxonidine
Nicorandil
Nitrates
Cordilox MR may decrease the breakdown of the following drugs in the liver causing to increase the amount of these drugs in the blood:
Atorvastatin
Buspirone
Carbamazepine
Ciclosporin
Digoxin
Eplerenone
Midazolam
Simvastatin
Sirolimus
Tacrolimus
Theophylline
The following drugs may increase the removal of Cordilox MR from the body and could make it less effective:
Phenobarbital
Phenytoin
Rifampicin
Herb St John's wort
If Cordilox MR is taken in combination with lithium the level of lithium in the blood may decrease.
Cordilox MR Overdose
Cordilox MR overdose symptoms include nausea, vomiting, dizziness, low blood pressure and other heightened side effects symptoms.
In case of Cordilox MR overdose, seek medical attention right away.
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