Gamithromycin: Veterinary drug

Gamithromycin solution for injection for cattle is the antibiotic. Gamithromycin is used in cattle to treat or to prevent Bovine Respiratory Disease (BRD) caused by the bacteria Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. When using Gamithromycin to prevent BRD the presence of the disease in the herd should be established first. Gamithromycin is given as a single subcutaneous (under the skin) injection. The dose to use is calculated based on the weight of the animal being treated. Animals weighing more than 550 lbs.(250 kg) will need to be injected at more than one site. Gamithromycin works by blocking the bacteria’s ribosomes, which are the parts of the cells where proteins are produced, and consequently inhibiting the growth of bacteria. Gamithromycin has been shown to be efficacious in the treatment and prevention of BRD, associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. In the treatment of BRD Gamithromycin has been shown to be as effective as tulathromycin.

GAMITHROMYCIN SIDE EFFECTS


After injection of Gamithromycin, up to 45% of animals will show some swelling at the site of injection. The animals may also show some signs of slight pain for one day. The swelling generally resolves in 3 to 14 days but may persist in some animals for up to 35 days after treatment.

Gamithromycin: Precautions for Humans



People with known hypersensitivity (allergy) to similar antibiotics (macrolide class) should avoid contact with Gamithromycin. Gamithromycin may cause irritation to the eyes or the skin. Therefore, contact with skin or eyes should be avoided. If Gamithromycin comes in direct contact with the eyes, they should be flushed immediately with clean water.

Similarly, if Gamithromycin comes into direct contact with skin the affected area should be washed immediately with clean water. In case of accidental self-injection, medical advice should be sought immediately and the package leaflet or the label should be presented to the physician.



Gamithromycin: Withdrawal Period



After the last administration of Gamithromycin, cattle should not be slaughtered for 64 days.

Gamithromycin: Milk Consumption



As the safety of Gamithromycin in breeding animals has not been studied, the drug should not be used in lactating cows or heifers producing milk for human consumption. Gamithromycin should also not be used in pregnant cows or heifers which are intended to produce milk for human consumption within 2 months of calving.

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