Xenical Side Effects, Overdose and Pregnancy Information

Xenical side effects may include allergic reactions like skin rash or hives, arthritis, back pain, and blood in the urine. Other Xenical side effects include breathing problems, dark urine, flu-like symptoms, loss of appetite, nausea, vomiting, urgent bowel movements, fatigue, yellowing of the eyes or skin, swelling of the face, lips, or tongue, and stomach pain.

Xenical Side Effects Reporting

If you experience any Xenical side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

Xenical is a type of drug known as a lipase inhibitor. Xenical is used to aid weight loss in people who are overweight or obese. Main ingredient in Xenical is orlistat. Xenical is not absorbed into the bloodstream, but works in the stomach and small intestine, where it prevents the working of two digestive enzymes known as gastric and pancreatic lipases. One Xenical capsule is taken three times a day at mealtimes to prevent fat from being absorbed by the body. This deprives the body from using the fat as a source of energy, or converts it into fat tissue resulting in weight loss.

Xenical Warning and Caution

Xenical should not be given to people with chronic malabsorption syndrome.

People in whom the flow of bile from the liver to the intestines is blocked (cholestasis).

Xenical should be taken immediately before, during, or up to one hour after each main meal. If a meal is missed, or contains no fat, you should leave out the dose. This is because Xenical will have no effect if no fat has been consumed.

Do not take more than three Xenical capsules per day.

As Xenical works by preventing the absorption of fat, you are more likely to experience digestive side effects such as gas, sudden bowel motions, and soft, fatty or oily stools, if you take Xenical with a meal that is very high in fat.

Xenical may potentially impair the absorption of fat-soluble vitamins (A,D,E,K).

If you experience severe or persistent rectal bleeding while taking Xenical you should consult your physician.

Xenical can cause diarrhea, which if severe, can reduce the effectiveness of oral contraceptive pills.

Xenical should not be given to children under 18 years of age.

Xenical should be used with caution in people with:

Long-term kidney disease.

Diabetes. (If you have diabetes, weight loss may be accompanied by an improvement in your blood sugar levels, in which case your dose of antidiabetic drug may then need to be adjusted).

Hypothyroidism.

Epilepsy.

Xenical and Pregnancy

Xenical should not be used during pregnancy. Nursing mothers should switch to bottle-feed while using Xenical.

Xenical Interaction

Xenical should not be used in combination with the following:

Acarbose

Ciclosporin

People taking anti-blood-clotting medicines (such as warfarin)

Xenical may decrease the blood level of amiodarone.

If you are taking medicines for diabetes, you may need an adjustment in your dose if you lose weight while taking Xenical. This is because weight loss may be accompanied by an improvement in your blood sugar levels.

If you are taking medicines for high blood pressure or high cholesterol levels, you may need an adjustment in your dose if you lose weight while taking Xenical. This is because your weight loss may be accompanied by an improvement in your blood pressure or cholesterol levels.

Xenical may possibly reduce the absorption of levothyroxine (taken for an underactive thyroid gland).

Xenical may possibly reduce the absorption of antiepileptic medicines such as valproate or lamotrigine.

If you take a multivitamin supplement with this medicine, it should be taken at least two hours after your Xenical dose, or at bedtime, as otherwise the Xenical will prevent the vitamins being absorbed.

Xenical Overdose

In case of Xenical overdose seek medical attention right away.

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