Accolate Side Effects, Overdose and Pregnancy Information

Accolate is a leukotriene receptor antagonist used to treat asthma as well as to relieve the stuffy, runny nose and sneezing caused by seasonal allergies and hay fever. Main ingredient in Accolate is Zafirlukast. Leukotrienes are chemicals that occur naturally in the body that cause inflammation during asthma and seasonal allergies. Accolate helps in the attack by blocking leukotreine from binding to tissue receptors; it is the binding to these tissues that stimulates the cells to cause inflammation. Accolate can reduce the frequency of asthma attack, if taken on a regular basis. However, Accolate does not help during an asthma attack. Other fast action asthma drugs should be taken during an acute attack. Accolate starts working in about 3-14 days.

Accolate Side Effects

Accolate side effects include headache, dizziness, upset stomach, and allergic reactions. Other Accolate side effects may include bronchitis, bruising, cough, drowsiness, fatigue, insomnia, irritability, itching, rash, restlessness, nausea, and vomiting.

Accolate Side Effects Reporting

If you experience any Accolate side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

ACCOLATE WARNING

Accolate should NOT be used during an asthma attack.

ACCOLATE INTERACTIONS

Check with your physician before combining Accolate with the following:

Blood thinners

Certain antibiotics like erythromycin

Phenobarbital Rifampin

Aspirin increases the amount of Accolate in the blood.

ACCOLATE AND PREGNANCY

Accolate should only be used during pregnancy if considered necessary. If you are or planning to become pregnant, inform your physician right away.

To be on the safe side, nursing mothers should switch to bottle-feed while taking Accolate.

ACCOLATE DOSES

ADULTS AND CHILDREN (age 12 and up) 20 mg twice daily, at least an hour before meal.

CHILDREN (age 5-11) 10 mg twice daily.

CHILDREN (age 2-5)

4 mg chewable/evening.

ACCOLATE OVERDOSE

Little is known about the effects of an overdose caused by Accolate.

If you suspect an overdose, seek medical help right away.
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