Celebrex Side Effects, Overdose and Pregnancy Information

Celebrex side effects may include headaches, diarrhea, nausea, respiratory infection, sinus inflammation, back pain, dizziness, insomnia, rash, runny nose, sore throat, and swelling. Less common Celebrex side effects may include allergic reactions, anxiety, blisters in mouth and eyes, blood disorders and infections, blurred vision, bone disorders, breast pain, breast problems, bronchitis, cataracts, chest pain, and colitis. Other Celebrex side effects may include conjunctivitis, constipation, coughing, deafness, depression, dermatitis, diabetes, difficult urination, difficulty breathing, difficulty swallowing, drowsiness, dry mouth, dry skin, earache, ear infection, ear ringing, eye infection, eye pain, fainting, fatigue, fever, flu symptoms, and fungal infection.

Rare Celebrex side effects may include gallstones, gangrene, general swelling, glaucoma, hair loss, heart failure, heart irregularities, hemorrhoids, hepatitis, hives, hot flashes, increased appetite, increased blood pressure, increased heart rate, increased muscle tone, increased urination, pneumonia, poor coordination, prostate problems, severe skin rash and peeling, skin reaction due to sunlight, skin sensitivity, skin tingling, stroke, suicide, sweating, swollen face and throat, taste disturbances, tendonitis, tiredness, tooth disorders, urinary incontinence, urinary tract infections, vaginal problems, vomiting, weakness, and weight gain.

Celebrex Side Effects Reporting

If you experience any Celebrex side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

Celebrex is a new type of Non-Steroidal Anti-Inflammatory drugs (NSAIDs) called COX-2 inhibitors given for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis and rheumatoid arthritis. Celebrex fights pain and inflammation by inhibiting the effect of a natural enzyme called COX-2. Unlike the traditional NSAIDs, Celebrex does not interfere with a stomach protecting COX-1. Because of that Celebrex is less likely to cause the bleeding and ulcers that comes with continued use of the traditional NSAIDs like Naproxen or Ibuprofen. Celebrex has also been effective in reducing the number of colorectal polyps in people who suffer from the condition called FAP (Familial Adenomatous Polyposis). Although Celebrex is easy on the stomach, it still poses risk to those who have had stomach ulcer or gastrointestinal bleeding in the past. If you are one of them, make sure your physician is aware of it.

CELEBREX OVERDOSE

Symptoms of Celebrex overdose may include heart attack, breathing difficulties, coma, drowsiness, gastrointestinal bleeding, high blood pressure, kidney failure, nausea, sluggishness, stomach pain, and vomiting. In case of Celebrex overdose, seek medical help right away. If you miss a dose of Celebrex, take it as soon as you can. However, if it is just about time for your next dose, skip the one you forgot and go on with your regular schedule. Never take a double dose of Celebrex.

CELEBREX AND PREGNANCY

Celebrex has caused birth defects in animals studies and it may cause fetal heart development in later part of pregnancy. Celebrex may pass into breast milk and nursing mothers should switch to bottle-feed while taking Celebrex.

CELEBREX WARNING

Pfizer has issued a warning against Celebrex. This action was taken after patients enrolled in a large clinical trial who were taking Celebrex for another reason than pain relief, suffered both fatal and non fatal heart attacks.

Depending on your individual risk factors and your personal preference, your doctor may recommend some alternatives to Celebrex. Options include switching back to an older class of drugs like ibuprofen or naproxen.

Do not take Celebrex if you are allergic to sulfonamide drugs such as sulfadiazine, sulfisoxazole, Gantanol, and Thiosulfil. Also avoid Celebrex if you've ever suffered an asthma attack, face and throat swelling, or skin eruptions after taking aspirin or other NSAIDs.

If you are taking a steroid medication for your arthritis pain, do not stop using it suddenly when you begin therapy with Celebrex. Celebrex is not an alternative for such drugs.

Celebrex has been known to cause kidney or liver problems, particularly in people with an existing condition. If you have such a disorder, inform your doctor before using Celebrex. If you have anemia, make sure the physician knows about it. Celebrex occasionally advances this problem.

Celebrex sometimes causes water retention, which can make worse swelling, high blood pressure, and heart failure. Use Celebrex with caution if you have any of these conditions.

Celebrex is not recommended for children under 18.

CELEBREX INTERACTION

Do not combine Celebrex with herbs like feverfew, garlic, ginseng and ginkgo as they may interfere with clotting.

Check with your physician before combining Celebrex with the following:

ACE-inhibitors
Aspirin: Let your doctor know if you take low-dose aspirin to protect against heart attack. Aspirin increases your risk of stomach ulcers or bleeding.Blood thinning drugs and supplements like Lecithin or Fish oil.
Fluconazole
Furosemide
Lithium
Thiazide diuretics.

CELEBREX DOSES

ADULTS
For osteoarthritis 100mg twice daily or a single doe of 200mg. For rheumatoid arthritis 100 to 200mg twice daily. For FAP and menstrual cramps 400mg twice daily.

Reduced dosage is recommended for people with liver problems.

CHILDREN
Celebrex is not recommended for children under 18.
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