Megace Side Effects, Overdose and Pregnancy Information


Megace is given to treat premenstrual syndrome (PMS), absence of menstruation, prevent premature labor, abnormal uterine bleeding and in combination with ERT (estrogen replacement therapy) to prevent estrogen from thickening and abnormal growth of the lining of the uterus. Megace is also given to people including men suffering from sleep apnea to stimulate breathing.Main ingredient in Megace is Megestrol. Megace is derived from the progesterone which is the main hormone involved in the pregnancy. Progesterone helps the womb to accept the fertilized egg as well as maintaining the growth of the fetus. Progesterone regulates other hormones to start and stop the menstrual cycle.




Megace Side Effects


Megace side effects include abdominal pain, acne, blood clot in a vein, lungs, or brain, breakthrough bleeding, breast tenderness, increase in blood pressure, depression, dry mouth, insomnia, headache, rash, itching, spotting, loss of appetite, fatigue, nausea, gain or loss of body hair and water retention. Other Megace side effects may include dizziness and sensitivity to the sun. Do not drive a car or operate machinery until you know how Megace affects you.

Megace Side Effects Reporting


If you experience any Megace side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

MEGACE CAUTION



Megace should not be used during the first 4 months of pregnancy; as this could result in birth defects.

Avoid using Megace if you are allergic or sensitive to any progestin.

Avoid using Megace if you have a history of asthma, blood clot, depression, diabetes, epilepsy, high cholesterol, stroke, kidney or liver disease, varicose veins, heart problems, breast cancer, genital cancer, osteoporosis, undiagnosed vaginal bleeding or miscarriage.

MEGACE INTERACTION



Check with your doctor before combining Megace with the following

-Aminoglutethimide
-Carbamazepine
-Phenobarbital
-Phenytoin
-Rifabutin
-Rifampin

MEGACE AND PREGNANCY



Avoid using Megace during pregnancy. It may cause birth defects especially during the first 4 months of pregnancy.

Megace appears in breast milk. If you are nursing switch to bottle-feed while taking Megace.

MEGACE DOSES



Megace dosage will depend on the medical condition being treated.

If Megace upsets your stomach, take it with food.

MEGACE OVERDOSE


Megace overdose symptoms may include enhanced side effects. If you suspect Megace overdose seek medical help right away.

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