Megestrol is derived from the progesterone which is the main hormone involved in the pregnancy. Progesterone helps the womb to accept the fertilized egg as well as maintaining the growth of the fetus. Progesterone regulates other hormones to start and stop the menstrual cycle. Megestrol is given to treat premenstrual syndrome (PMS), absence of menstruation, prevent premature labor, abnormal uterine bleeding and in combination with ERT (estrogen replacement therapy) to prevent estrogen from thickening and abnormal growth of the lining of the uterus. Megestrol is also given to people including men suffering from sleep apnea to stimulate breathing.
CAUTION
Megestrol should not be used during the first 4 months of pregnancy; as this could result in birth defects.
Avoid using Megestrol if you are allergic or sensitive to any progestin.
Avoid using Megestrol if you have a history of asthma, blood clot, depression, diabetes, epilepsy, high cholesterol, stroke, kidney or liver disease, varicose veins, heart problems, breast cancer, genital cancer, osteoporosis, undiagnosed vaginal bleeding or miscarriage.
SIDE EFFECTS OF MEGESTROL
Common side effects of Megestrol may include abdominal pain, acne, blood clot in a vein, lungs, or brain, breakthrough bleeding, breast tenderness, increase in blood pressure, depression, dry mouth, insomnia, headache, rash, itching, spotting, loss of appetite, fatigue, nausea, gain or loss of body hair and water retention.
Megestrol may cause dizziness. Do not drive a car or operate machinery until you know how Megestrol affects you.
Megestrol may also increase sensitivity to the sun.
MEGESTROL INTERACTION
Check with your doctor before combining Megestrol with the following
-Aminoglutethimide
-Carbamazepine
-Phenobarbital
-Phenytoin
-Rifabutin
-Rifampin
MEGESTROL AND PREGNANCY
Avoid using Megestrol during pregnancy. It may cause birth defects especially during the first 4 months of pregnancy.
Megestrol appears in breast milk. If you are nursing switch to bottle-feed while taking Megestrol.
MEGESTROL DOSES
Dosage will depend on the medical condition being treated.
If Megestrol upsets your stomach, take it with food.
MEGESTROL OVERDOSE
Megestrol overdose symptoms may include enhanced side effects. If you suspect an overdose frm Megestrol, seek medical help right away.
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