Nitro-Dur is given for the prevention and treatment for chest pain
(angina pectoris). Nitro-Dur helps improve oxygen supply by relaxing the
walls of blood vessels, resulting in their dilation and reducing the
workload of the heart. Main ingredient in Nitro-Dur is Nitroglycerin. There are various types of Nitro-Dur, sublingual, ointment, spray,sustained release capsules or tablets or patches. Depending on its type
they are used to prevent an attack of angina, relieve or to reduce the
frequency of such attacks.
Nitro-Dur Side Effects
Nitro-Dur side effects include dizziness, headache, light-headedness, worsened angina pain and flushing. Rare Nitro-Dur side effects may include dry mouth, diarrhea, fainting, heart pounding, low blood pressure, nausea, vomiting, pallor, restlessness, severe allergic reactions, rash, sweating, vertigo, fatigue, and numbness.
Nitro-Dur Side Effects Reporting
If you experience any Nitro-Dur side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.
Inform your physician about any medical condition that you already have
before using Nitro-Dur. These conditions include previous or recent
heart attack, stroke, kidney or liver problems, head injury, anemia,
glaucoma, hyperthyroidism and low blood pressure.
Nitro-Dur may cause severe low blood pressure, dizziness and
fainting. Do not drive a car or operate machinery until you know how
Nitro-Dur affects you.
Avoid using Nitro-Dur if you are allergic to nitrates or nitrites or
to the adhesive in the patch.
Nitro-Dur capsule should not be used if you have closed-angle
glaucoma or postural hypotension.
Avoid using the Nitro-Dur tablets if you are using drugs for erectile
Contact your physician right away if your vision becomes blurry or you
experience dry mouth while taking Nitro-Dur.
Nitro-Dur may cause extreme low blood pressure when combined with
high blood pressure medicines such as:
Nitro-Dur may also cause a severe drop in blood pressure when taken
with the impotence drug such as sildenafil (Viagra) or similar drugs.
Aspirin and other NSAIDs may enhance the effects of Nitro-Dur.
Alcohol may cause a sudden decrease in blood pressure when combined
Inform your doctor if you are using any herbs that may increase or
decrease blood pressure such as ginseng, hawthorn, saw palmetto etc.
NITRO-DUR AND PREGNANCY
The effects of Nitro-Dur on pregnancy have not been established.
If you are, or planning to become pregnant, inform your physician
before starting Nitro-Dur.
Nitro-Dur does pass into breast milk. Nursing mothers should switch
to bottle-feed while using Nitro-Dur.
Sublingual or transmucosal tablets:
At the onset of the chest pain,
dissolve 1 tablet under the tongue or between cheek and gum. Repeat after
5 minutes if the pain does not subsides. However, if pain continues even
after 3 tablets, seek emergency medical help right away. Do not take more
than 3 tablets in 15 minutes.
Sustained-Release Tablets and Capsules:
1 capsule 2-4 times daily.
This type of Nitro-Dur should not be used during an attack.
1-2 sprays under the tongue; repeat as needed to relieve the
pain. However, if pain continues even after 3 doses in 15-minutes period,
seek emergency medical help right away.
For the prevention of angina attack, apply 1 patch every
24-hour period to hairless skin. Make sure to discard the used patch
properly away from children and pets as the leftover drug may cause harm
For prevention, apply 1-2 in. to a hairless skin every 4-8
hours. Rotate application sites to prevent skin inflammation or rash. Do
not rub or massage the skin.
Nitro-Dur overdose symptoms may include low blood pressure,
headache, bluish skin, dizziness, confusion, diarrhea, breathing
difficulty, fainting, fever, flushed skin, loss of appetite, nausea,
seizures, sweating, vertigo, visual disturbances, vomiting, paralysis, and
coma. In case of Nitro-Dur overdose seek emergency hospital help right
If you miss a dose of Nitro-Dur, take it as soon as you can. However,
if it is just about time for your next dose, skip the one you forgot and
go on with your regular schedule. Avoid taking a double dose.