Nitrostat Side Effects, Overdose and Pregnancy Information

Nitrostat is given for the prevention and treatment for chest pain (angina pectoris). Nitrostat helps improve oxygen supply by relaxing the walls of blood vessels, resulting in their dilation and reducing the workload of the heart. There are various types of Nitrostat, sublingual, ointment, spray, sustained release capsules or tablets or patches. Depending on its type they are used to prevent an attack of angina, relieve or to reduce the frequency of such attacks. Main ingredient in Nitrostat is Nitroglycerin.

Nitrostat Side Effects

Nitrostat side effects may include dizziness, headache, light-headedness, worsened angina pain and flushing. Rare Nitrostat side effects may include dry mouth, diarrhea, fainting, heart pounding, low blood pressure, nausea, vomiting, pallor, restlessness, severe allergic reactions, rash, sweating, vertigo, fatigue, and numbness.

Nitrostat Side Effects Reporting

If you experience any Nitrostat side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

NITROSTAT OVERDOSE

Nitrostat overdose symptoms may include low blood pressure, headache, bluish skin, dizziness, confusion, diarrhea, breathing difficulty, fainting, fever, flushed skin, loss of appetite, nausea, seizures, sweating, vertigo, visual disturbances, vomiting, paralysis, and coma. In case of Nitrostat overdose, seek medical help right away. If you miss a dose of Nitrostat, take it as soon as you can. However, if it is just about time for your next dose, skip the one you forgot and go on with your regular schedule. Never take a double dose of Nitrostat.

NITROSTAT CAUTION

Inform your physician about any medical condition that you already have before using Nitrostat. These conditions include previous or recent heart attack, stroke, kidney or liver problems, head injury, anemia, glaucoma, hyperthyroidism and low blood pressure.

Nitrostat may cause severe low blood pressure, dizziness and fainting. Do not drive a car or operate machinery until you know how Nitrostat affects you.

Avoid using Nitrostat if you are allergic to nitrates or nitrites or to the adhesive in the patch.

Nitrostat capsule should not be used if you have closed-angle glaucoma or postural hypotension.

Avoid using the Nitrostat tablets if you are using drugs for erectile dysfunction (impotence).

Contact your physician right away if your vision becomes blurry or you experience dry mouth while taking Nitrostat.

NITROSTAT INTERACTION

Nitrostat may cause extreme low blood pressure when combined with high blood pressure medicines such as:
Beta-blocker
Calcium channel blockers
isosorbide dinitrate
isosorbide mononitrate
blood vessel dilators

Nitrostat may also cause a severe drop in blood pressure when taken with the impotence drug such as sildenafil (Viagra) or similar drugs.

Aspirin and other NSAIDs may enhance the effects of Nitrostat.

Alcohol may cause a sudden decrease in blood pressure when combined with Nitrostat.

Inform your doctor if you are using any herbs that may increase or decrease blood pressure such as ginseng, hawthorn, saw palmetto etc.

NITROSTAT AND PREGNANCY

The effects of Nitrostat on pregnancy have not been established. If you are, or planning to become pregnant, inform your physician before starting Nitrostat. Nitrostat does pass into breast milk. Nursing mothers should switch to bottle-feed while using Nitrostat.

NITROSTAT DOSES

Sublingual or transmucosal tablets:
At the onset of the chest pain, dissolve 1 tablet under the tongue or between cheek and gum. Repeat after 5 minutes if the pain does not subsides. However, if pain continues even after 3 tablets, seek emergency medical help right away. Do not take more than 3 tablets in 15 minutes.

Sustained-Release Tablets and Capsules:
1 capsule 2-4 times daily. This type of Nitrostat should not be used during an attack.

Spray:
1-2 sprays under the tongue; repeat as needed to relieve the pain. However, if pain continues even after 3 doses in 15-minutes period, seek emergency medical help right away.

Patch:
For the prevention of angina attack, apply 1 patch every 24-hour period to hairless skin. Make sure to discard the used patch properly away from children and pets as the leftover drug may cause harm to them.

Ointment:
For prevention, apply 1-2 in. to a hairless skin every 4-8 hours. Rotate application sites to prevent skin inflammation or rash. Do not rub or massage the skin.
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