Ofloxacin Side Effects, Overdose and Pregnancy Information
Ofloxacin is given to treat infections of the lower respiratory system, urinary tract, sinuses, the skin, bones and joints, and prostate.
Ofloxacin is also used for inhalational anthrax, STDs, severe bronchial
infections, infectious diarrhea, typhoid fever, and pneumonia.
Ofloxacin belongs to the family of Flouroquinolone, which are
effective against many organisms that traditional antibiotics fail to
resist. Ofloxacin kills a variety of bacteria, and prevent them from
reproducing and is often used to treat infections all over the body.
However, they are not considered good to treat viral infections like flu.
Ofloxacin Side Effects
Ofloxacin side effects are nausea, vomiting and diarrhea.
Less common Ofloxacin side effects are abdominal pain, headache,
rash, and restlessness. Rare Ofloxacin side effects may include confusion, shortness of
breath, blood in urine, coughing up blood, depression, dizziness, hives,
irritability, liver and kidney failures.
Ofloxacin Side Effects Reporting
If you experience any Ofloxacin side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.
Symptoms of Ofloxacin overdose include confusion, delusion,
headache, upset stomach, and convulsions. In rare cases Ofloxacin
overdose may cause kidney failure. In case of Ofloxacin overdose seek
medical help right away.
If you miss a dose of Ofloxacin, take it as soon as you can. However, if it is just about time for your next dose, skip the one you forgot and go on with your regular schedule. Never take a double dose of Ofloxacin.
OFLOXACIN AND PREGNANCY
Animal studies have shown birth defects by Ofloxacin. Inform your
doctor if you are or planning to become pregnant before using Ofloxacin. Nursing mothers should switch to bottle-feed while taking Ofloxacin.
Stop taking Ofloxacin and seek medical help right away at the first
sign of a skin rash or any other allergic reaction. Though rare, serious
and seldom fatal allergic reactions have been reported, even after the
These reactions include loss of consciousness, swelling of the face and
throat, shortness of breath, hives, tingling, and rash.
You should not take Ofloxacin if you are sensitive to or have ever
had an allergic reaction to Ofloxacin or other antibiotics of this type
such as Ofloxacin, Noroxin and Trovan.
You should not drive a car, operate dangerous machinery, or participate
in any hazardous activity that requires full mental alertness until you
know how Ofloxacin affects you.
Continued or prolonged use of this drug may result in a growth of
bacteria that do not respond to this medication and can cause a secondary
If you have a known or suspected central nervous system disorder such
as epilepsy or hardening of the arteries in the brain, inform your
physician before taking Ofloxacin.
You should consult your doctor before taking Ofloxacin if you have
liver or kidney disease.
The following can interfere with the absorption of Ofloxacin:
Iron Supplements and other multivitamins
containing calcium, or zinc (also avoid taking milk or yogurt)
Serious and fatal reactions have occurred when Ofloxacin was taken
in combination with theophylline, Probeneacid and Cimetidine.
Ofloxacin may increase the effects of caffeine.
If Ofloxacin is taken with these drugs, the effects of either could
be increased or decreased:
For most infections 200-400 mg twice daily.
Doses of Ofloxacin may be reduced if the patient has kidney
Bacterial Conjunctivitis: (days 1-2) 1-2 drops in the infected eye every 2-4 hours.
(days 3-7) every 4-6 hours.
Bacterial Corneal Ulcer: (days 1-2) 1-2 drops every 30mins.
(days 3-9 or through the end) 1-2 drops every hour.
EARDROPS: 5-10 drops in the affected ear twice daily.
Ofloxacin is not recommended.