Pexeva Side Effects, Overdose and Pregnancy Information

Pexeva is given to treat depression that lasts for over 2 weeks, obsessive compulsive disorder (OCD), bulimia, anorexia, attention-deficit hyperactivity disorder (ADHD), borderline personality disorder, anxiety disorder, migraine and chronic headaches, post traumatic stress disorder, schizophrenia and social phobias. Main ingredient in Pexeva is Paroxetine Mesylate. Pexeva belongs to the family of drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs) that block the movement of the neurotransmitter (chemical messengers) serotonin into nerve endings. Serotonin is believed to govern moods and is quickly reabsorbed after its release at the nerve endings. SSRIs such as Pexeva slow this process, thus boosting the levels of serotonin in the brain. It usually takes 10-14 days for Pexeva to start working.

Pexeva Side Effects


Pexeva side effects may include suicidal thoughts, headaches, decreased sex drive, agitation, anxiety, nervousness, difficulty with ejaculation, dizziness, dry mouth, fatigue, upset stomach, appetite loss, insomnia, rash, sleepiness, and vomiting. Rare Pexeva side effects may include impotence, acne, abnormal dreams, low concentration, allergic reaction, hair loss, back pain, blindness, breast development in males, breast pain or enlargement, breathing difficulties, cataracts, chest pain, difficulty breathing, high blood pressure, hot flushes, inflammation of the penis, throbbing heartbeat, vaginal inflammation, hemorrhage, and urinary pain.

Pexeva Side Effects Reporting


If you experience any Pexeva side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.


PEXEVA WARNING



Unless the condition is significantly improved, possibility of suicide while taking Pexeva exists especially in severely depressed patients.

Pexeva is not recommended for children and teens as it could increase the risk of suicidal thoughts and behavior.

If you have a kidney or liver disorder, or have had seizures, your physician may limit your dosage. Caution is advised.

Pexeva may impair the ability to drive or operate machinery. Use caution until you know how the Pexeva affects you.

PEXEVA CAUTION



Do not take Pexeva within 2 weeks of taking any drug classified as an MAO inhibitor. Serious and sometimes fatal reactions can occur.

SSRIs like Pexeva should be used with caution by people with seizures.

Do not combine Pexeva with herbs like St.John's Wort, Kava, Hop, or Ginseng.

PEXEVA AND PREGNANCY



Pregnant women using SSRIs like Pexeva are more likely to deliver prematurely or going to have babies with major abnormalities.

Pexeva pass into breast milk. Nursing mothers should switch to bottle-feeding while Pexeva.

PEXEVA INTERACTION



There should be an interval of 2 weeks between stopping Pexeva and starting an MAOI antidepressant.

Do not drink alcoholic beverages while taking Pexeva. Use over-the-counter (OTC) medicines such as Aspirin, Ibuprofen, or Aleve with caution.

Do not combine Pexeva with herbs like St.John's Wort, Kava, Hop, or Ginseng.

It is imperative to check with your physician before combining Pexeva with the following:

Blood thinners
Cimetidine
Crystodigin
Flecainide
Imitrex
Lithium
MAO inhibitor drugs
Other serotonin-boosting drugs
Other antidepressants
Propafenone
Sumatriptan
Tolbutamide
Valium
Warfarin

PEXEVA DOSES



ADULTS
The usual starting dose is 20-60mg a day.
Seniors and people with liver or kidney condition may need a lower dose.

CHILDREN
Pexeva is not recommended for children and teens as it could increase the risk of suicidal thoughts and behavior.

PEXEVA OVERDOSE


Pexeva overdose symptoms include seizures, nausea, agitation, dizziness, rapid heartbeat, vomiting, coma, fainting, mania, and high or low blood pressure. In case of a Pexeva overdose, seek medical attention right away.

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