Promethazine Side Effects, Overdose and Pregnancy Information

Promethazine side effects include drowsiness, agitation, anxiety, headache, fatigue, indigestion, and dry mouth. Rare Promethazine side effects may include nausea, nervousness, cough, stuffy nose, and throat irritation.

Promethazine Side Effects Reporting

If you experience any Promethazine side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

Promethazine is the combination of antihistamine and decongestant (Pseudoephedrine) given to treat and relieve symptoms of seasonal allergies, common cold and flu as well as upper respiratory tract. The antihistamine in Promethazine relieves the symptoms of seasonal allergies and hay fever such as itchy, runny nose, sneezing, and watery eyes as well as symptoms of allergic reactions like hives or swelling. The decongestant (Pseudoephedrine) in Promethazine deals with constricting the blood vessels, which in turn reduces the blood, flow to the nasal passages thereby improving the flow of air and reducing nasal secretions. Main ingredients in Promethazine are Promethazine + Phenylephrine Hydrochloride.

PROMETHAZINE OVERDOSE

Symptoms of Promethazine overdose may include drowsiness, dizziness, nausea, nervousness, and dry mouth. In case of Promethazine overdose, seek medical help right away. If you miss a dose of Promethazine, take it as soon as you can. However, if it is just about time for your next dose, skip the one you forgot and go on with your regular schedule. Never take a double dose of Promethazine.

PROMETHAZINE AND PREGNANCY

Though generally considered safe, do not take Promethazine without the advice of your physician if you are or planning to become pregnant. Nursing mothers should switch to bottle-feed while taking Promethazine as it does pass into breast milk.

PROMETHAZINE CAUTION

Use caution when using Promethazine if you have high blood pressure, diabetes, heart disease, prostate problems, or hyperthyroidism as it contains the decongestant pseudoephedrine.

Avoid Promethazine if you have severe high blood pressure, glaucoma, or kidney disease.

Avoid taking Promethazine within 2 weeks of using an MAO-inhibitor.

Avoid Promethazine if you are allergic or sensitive to it.

May cause drowsiness or low concentration. Use caution when driving or operating machinery.

PROMETHAZINE INTERACTION

Promethazine should not be used within 2 weeks of using an MAO-inhibitor. Check with your physician before combining it with the following:

Beta-blockers
Mecamylamine
Methyldopa
Reserpine

Avoid Promethazine if you use a pacemaker and take digoxin.

Combining Promethazine with alcohol, tranquilizers, or narcotic analgesics may cause excessive drowsiness and low concentration.

PROMETHAZINE DOSES

Dosages vary for each individual. Consult your physician.
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