Rizatriptan Side Effects, Overdose and Pregnancy Information
Rizatriptan is given to treat migraine headaches in adults. Rizatriptan relieves the intensity of the pain and other symptoms including nausea, vomiting, and hypersensitivity to light, though it does not prevent nor reduce the frequency of attacks. Rizatriptan can also be used for cluster headaches. Migraine is believed to be caused by swollen or dilated blood vessels; Rizatriptan acts on neurotransmitter serotonin (5HT) receptors in the brain by narrowing those blood vessels. Rizatriptan usually takes about an hour to relieve the symptoms. Rizatriptan should only be given when the pain from migraine attack does not respond to regular pain killers like Aspirin, Acetaminophen (paracetamol) or Ibuprofen.
Rizatriptan Side Effects
Rizatriptan side effects may include dizziness, nasal discomfort, muscle weakness, nausea, neck pain, numbness, vomiting and temporary rise in blood pressure. Rare Rizatriptan side effects include severe allergic reactions, anxiety, asthma, agitation, changes in heart rhythm, confusion, constipation, cough, depression, difficult or painful urination, fatigue, pressure in chest, rapid and throbbing heartbeat, rash, ringing in the ears, tightness in chest, tremors, and vision changes.
Rizatriptan Side Effects Reporting
If you experience any Rizatriptan side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.
RIZATRIPTAN WARNING
Rizatriptan should not be given to those with high blood pressure or who have or are at risk of heart disease or condition. It should also not be used if you have liver or kidney disease.
Rizatriptan must not be given for 2 weeks after taking an MAO inhibitor drug such as the antidepressants Nardil and Parnate.
If you develop severe chest pain after taking Rizatriptan, seek medical help right away.
Rizatriptan injections should not be injected into a vein. This could result in a serious heart irregularity.
Though rarely, severe and fatal allergic reactions have occurred in people taking Rizatriptan. In rare cases, people taking Rizatriptan have suffered seizures.
RIZATRIPTAN AND PREGNANCY
If you are pregnant or planning to become pregnant, inform your physician before taking Rizatriptan as animal studies have shown damage to fetus. Nursing mothers should switch to bottle-feed while taking Rizatriptan.
RIZATRIPTAN INTERACTION
Check with your doctor before combining Rizatriptan with the following:
Drugs classified as MAO inhibitors
Ergot-containing drugs such as Cafergot and Ergostat
Luvox
Paxil
Prozac
Zoloft
RIZATRIPTAN DOSES
Rizatriptan is not recommended for children under 18.
RIZATRIPTAN TABLETS
The usual adult dose is 5-10mg tablet taken with meal or milk. For better results Rizatriptan should be taken right at the onset of the pain. If one Rizatriptan does not respond, you can take second dose at least 2 hours after taking the first one. The maximum dose for a day should not exceed 30mg.
Those with liver disease should take lower doses of Rizatriptan Tablets.
RIZATRIPTAN OVERDOSE
Rizatriptan overdose symptom may include convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor, nausea and vomiting.
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