Simvastatin Side Effects, Overdose and Pregnancy Information

Simvastatin side effects may include headache, abdominal pain, constipation, cramps,and decreased sex drive. Other Simvastatin side effects include depression, diarrhea, fatigue, insomnia, vomiting, weakness, and weight loss.

SIMVASTATIN SIDE EFFECTS REPORTING

If you experience any Simvastatin side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

Simvastatin is given to reduce cholesterol and fatty substances called triglyceride in the body. Simvastatin works by clearing harmful low density lipoprotein (LDL) cholesterol out of the blood and by limiting the body's ability to form new LDL cholesterol. For those who are at high risk of heart disease, the physician may suggest a cholesterol-lowering drug if LDL readings are 130 or higher. For those at low risk, Simvastatin is considered at readings of 190 or more. Simvastatin is usually prescribed only if diet and exercise fail to bring the desired cholesterol levels. Buildup of Cholesterol along the walls of the arteries decreases blood flow and oxygen supply to the heart, brain and other vital organs resulting in heart disease, hypertension, and stroke. It could take up to 6 weeks before the desired level is achieved.

SIMVASTATIN OVERDOSE

If you suspect Simvastatin overdose, seek medical attention right away. If you miss a dose of Simvastatin, take it as soon as you can. However, if it is just about time for your next dose, skip the one you forgot and go on with your regular schedule. Never take a double dose of Simvastatin.

SIMVASTATIN AND PREGNANCY

Simvastatin must not be used during pregnancy. Nursing mothers should switch to bottle-feed while using Simvastatin.

Simvastatin Caution

Simvastatin should not be given during pregnancy or while nursing. Tell your doctor if you or anyone in your family liver disease or diabetes.

Simvastatin could cause damage to muscle tissue, so be sure to tell your physician right away if you notice any unusual muscle pain or weakness.

Simvastatin Interactions

Simvastatin should not be combined with following:

Amiodarone, Biaxin, Clofibrate, Erythromycin, Fenofibrate ,Itraconazole, Ketoconazole, Neoral, Niacin, Nizoral, Protease inhibitors, Sporanox, Tricor.

Check with your physician before combining Simvastatin with any of the following:Antacids
Erythromycin
Oral contraceptives
Herbs like ephedra, ginseng and saw palmetto.
Grape juice may slow down the breakdown of Simvastatin in the liver.

Simvastatin Doses

Only your physician can determine the dose. Generally, for adults the starting dose is 5-80mg(5-20mg for Seniors) once a day. Simvastatin usually begins working within 2 weeks.

If you miss a dose, take the missed dose of Simvastatin as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.
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