Sumatriptan Side Effects, Overdose and Pregnancy Information

Sumatriptan side effects include dizziness, nasal discomfort, muscle weakness, nausea, neck pain, numbness, vomiting and temporary rise in blood pressure. Rare Sumatriptan side effects may include severe allergic reactions, anxiety, asthma, agitation, changes in heart rhythm, confusion, constipation, cough, depression, difficult or painful urination, fatigue, pressure in chest, rapid and throbbing heartbeat, rash, ringing in the ears, tightness in chest, tremors, and vision changes.

SUMATRIPTAN SIDE EFFECTS REPORTING

If you experience any Sumatriptan side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

Sumatriptan is given to treat migraine headaches in adults. Sumatriptan relieves the intensity of the pain and other symptoms including nausea, vomiting, and hypersensitivity to light, though it does not prevent nor reduce the frequency of attacks. Sumatriptan can also be used for cluster headaches. Migraine is believed to be caused by swollen or dilated blood vessels; Sumatriptan acts on neurotransmitter serotonin (5HT) receptors in the brain by narrowing those blood vessels. Sumatriptan usually takes about an hour to relieve the symptoms. Sumatriptan should only be given when the pain from migraine attack does not respond to regular pain killers like Aspirin, Acetaminophen (paracetamol) or Ibuprofen.

SUMATRIPTAN OVERDOSE

Sumatriptan overdose symptoms may include convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor, nausea and vomiting. In case of Sumatriptan overdose, seek medical help right away. If you miss a dose of Sumatriptan, take it as soon as you can. However, if it is just about time for your next dose, skip the one you forgot and go on with your regular schedule. Never take a double dose of Sumatriptan.

SUMATRIPTAN AND PREGNANCY

If you are pregnant or planning to become pregnant, inform your physician before taking Sumatriptan as animal studies have shown damage to fetus. Nursing mothers should switch to bottle-feed while taking Sumatriptan.

SUMATRIPTAN WARNING

Sumatriptan should not be given to those with high blood pressure or who have or are at risk of heart disease or condition. It should also not be used if you have liver or kidney disease.

Sumatriptan must not be given for 2 weeks after taking an MAO inhibitor drug such as the antidepressants Nardil and Parnate.

If you develop severe chest pain after taking Sumatriptan, seek medical help right away.

Sumatriptan injections should not be injected into a vein. This could result in a serious heart irregularity.

Though rarely, severe and fatal allergic reactions have occurred in people taking Sumatriptan. In rare cases, people taking Sumatriptan have suffered seizures.

SUMATRIPTAN INTERACTION

Check with your doctor before combining Sumatriptan with the following:

Drugs classified as MAO inhibitors
Ergot-containing drugs such as Cafergot and Ergostat
Luvox
Paxil
Prozac
Zoloft

SUMATRIPTAN DOSES

Sumatriptan is not recommended for children under 18.

SUMATRIPTAN INJECTION

The maximum single recommended adult dose is 6mg injected under the skin. Injection should not be given intravenous.

The maximum dose that may be given within 24 hour period is two 6mg injections taken at least 1 hour apart.

SUMATRIPTAN TABLETS

The usual adult dose is one 25-100mg tablet taken with meal or milk. The maximum dose for a day should not exceed 200mg.

Those with liver disease should not take more than 50mg of Sumatriptan Tablets at one time.

SUMATRIPTAN NASAL SPRAY

The recommended adult dose ranges from 5-20mg taken at the onset of the attack and repeated once, if necessary, 2 hours later. Doses are usually taken as a single spray in one nostril, but if a 10mg dose works best for you, you can take it as a 5mg spray in each nostril. Do not use more than 20mg at a time, or take more than 40 mg per day.
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