Theophylline Side Effects, Overdose and Pregnancy Information

Theophylline side effects are nervousness, restlessness, nausea, vomiting, headache, diarrhea, irritability, insomnia, seizures, rash, and fatigue. Rare side effects of Theophylline include arrhythmia, convulsions and even death.

THEOPHYLLINE SIDE EFFECTS REPORTING


If you experience any Theophylline side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

Theophylline is an Xanthine bronchodilator, a type of drug used to treat shortness of breath, other breathing problems related to asthma, chronic bronchitis, emphysema and wheezing. Theophylline improves the flow of air through the lungs by relieving and opening the bronchial airways and tubes.



THEOPHYLLINE CAUTION



Xanthine bronchodilators like Theophylline may cause nervousness. Do not drive a car or operate machinery until you know how Theophylline affects you.

Before using Theophylline, inform your physician if you have heart disease, high blood pressure, arrhythmia, stomach ulcer, kidney or liver disease, seizures or thyroid disease.

THEOPHYLLINE INTERACTION



Check with your physician before combining Theophylline with the following:

-Beta-blockers-Calcium channel blockers-Flu vaccine-Allopurinol-Oral contraceptives-Antihistamine-Barbiturates-Charcoal-Caffeine-Cimetidine-Cortisteroids-Diltiazem-Disulfiram-Ephedrine-Erythromycin-Fluvoxamine-Interferon-Ketoconazole-Lansoprazole-Lithium-Methotrexate-Mexiletine-Prednisone-Rifampin-Tobacco-Tacrolimus-Verapamil-Zafirlukast-Zileuton

Herbs that may increase blood pressure such as ephedra, Ginseng, Kola, Saw palmetto, St.John's wort as well as Tea, Coffee, coke, and chocolate.

THEOPHYLLINE AND PREGNANCY



Though Xanthine bronchodilators like Theophylline do not cause birth defects, if you are or planning to become pregnant discuss the pros and cons of using Theophylline during pregnancy with your doctor.

Nursing mothers should switch to bottle-feed as Theophylline may pass into breast milk and may make infants nervous, irritable and may also cause insomnia.

THEOPHYLLINE DOSES



Infants 6-52 weeks:Your physician will determine the dosage.

Children 1-8:Up to 10.8 mg/lb. of body weight/day.

Children 9-11:Up to 9 mg/lb. of body weight/day.

Children 12-16:Up to 8.1 mg/lb. of body weight/day.

Adults: Up to 6 mg/ lb. of body weight every 6-8 hours. Maximum dose is 900 mg/day.

THEOPHYLLINE OVERDOSE


Theophylline overdose symptoms are loss of appetite, nausea, vomiting, nervousness, insomnia, headache, arrhythmia, extreme thirst, and convulsion. In case of Theophylline overdose; seek emergency medical help right away. If you miss a dose of Theophylline, take it as soon as you can. However, if it is just about time for your next dose, skip the one you forgot and go on with your regular schedule. Avoid taking a double dose of Theophylline.

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