Prinivil Side Effects, Overdose and Pregnancy Information

Prinivil side effects include cough, dizziness, headache, sleep interruptions, hypotension, diarrhea, vomiting, and problems with kidney functions. Rare Prinivil side effects may include fatigue, weakness, nausea, indigestion, itching, mood swings, insomnia, palpitations, enhanced level of potassium in the blood (hyperkalaemia), dry mouth, confusion, swelling of lips, face, tongue or throat, hair loss and severe allergic skin reactions.

PRINIVIL SIDE EFFECTS REPORTING

If you experience any Prinivil side effects not mentioned above you should report it to your primary health care provider or FDA 1-800-FDA-1088 in the United States, Health Canada 1-866-225-0709 in Canada, MHRA 020 3080 6000 in UK, or TGA 1800 020 653 in Australia.

Prinivil is a type of drug known as ACE inhibitor. Prinivil is primarily used to lower blood pressure. Prinivil can also be used to improve the symptoms of heart failure and to improve survival following a heart attack. Prinivil works by blocking the action of a compound in the body called Angiotensin converting enzyme (ACE). ACE produces another compound called Angiotensin II, which causes blood vessels to tighten and narrow resulting in increasing the pressure within the blood vessels. Prinivil blocks the action of ACE by reducing the production of Angiotensin II. This means that the blood vessels are allowed to relax and expand.

PRINIVIL OVERDOSE

Prinivil overdose symptoms may include extreme dizziness, light-headedness and or fainting. In case of Prinivil overdose, seek medical attention right away. If you miss a dose of Prinivil, take it as soon as you can. However, if it is just about time for your next dose, skip the one you forgot and go on with your regular schedule. Never take a double dose of Prinivil.

Prinivil Warning

Some people may experience dizziness caused by low blood pressure in the first few days of taking Prinivil and especially the first dose. For this reason, the first dose should preferably be taken at night before going to bed.

Alcohol may enhance the blood pressure lowering effect of Prinivil, which can increase dizziness and may increase the risk of fainting.

ACE inhibitors like Prinivil can sometimes cause an allergic reaction called angioedema. Stop taking Prinivil and consult your physician right away if you experience difficulty breathing or swallowing, or swelling of your face, lips, tongue, throat, hands, feet or ankles while taking Prinivil.

Your blood pressure, kidney function and the amount of Potassium in your blood should be regularly monitored while you are taking Prinivil.

Prinivil should not be given to:

People who are allergic to other ACE inhibitors.

History of swelling of the lips, face or tongue with no known cause, or caused by previous use of an ACE inhibitor.

Pregnant women.

Prinivil is not recommended for children.

Prinivil should not be used if you are allergic to one or any of its ingredients.

Prinivil Caution

Prinivil should be used in caution with:

Seniors.

Decreased kidney function.

Narrowing of the arteries that supply blood to the kidneys.

People with low fluid volume or salt levels in the body, e.g. due to diuretic therapy, low-sodium diet, diarrhea or vomiting.

People taking other drugs for hypertension, specially diuretics.

Low blood pressure.

Severe heart failure.

Narrowing of the main artery of the body.

Diseases affecting connective tissue, e.g. scleroderma, rheumatoid arthritis.

People with kidney failure requiring a certain type of dialysis (high-flux membrane).

People receiving therapy to remove certain types of fat from the blood using a machine (LDL aphaeresis).

People undergoing therapy to decrease allergy to bee or wasp stings.

Prinivil Interaction

Prinivil may enhace effects of other drugs that lower blood pressure.

Prinivil may cause a large drop in blood pressure with the first dose in people taking antihypertensive drugs, especially those taking diuretic drugs.

If you are taking a diuretic drug, your physician may reduce your dose or ask you to stop taking it for a few days before starting Prinivil.

Inform your physician if you frequently feel dizzy while taking Prinivil in combination with other drugs that can lower blood pressure.

Other drugs that lower blood pressure include:
Other ACE inhibitors
Alpha-blockers
Angiotensin II receptor
Antipsychotics
Beta-blockers
Calcium-channel blockers
Diuretics
Dopamine agonists
MAOI antidepressants
Nitrates

NSAIDs such as Aspirin, Acetaminophen, and Ibuprofen may reduce the blood pressure lowering effect of Prinivil and may increase the risk of a decline in kidney function.

There may be a risk of raised potassium levels in the blood (hyperkalaemia) if the following drugs are taken with Prinivil:
Angiotensin II receptor antagonists
Potassium-containing salt substitutes
Potassium salts
Potassium -sparing diuretics
Potassium supplements.

Prinivil may increase the blood level of lithium and for this reason, it is not normally recommended for people taking lithium.

Prinivil may possibly enhance the blood sugar lowering effect of Insulin and oral antidiabetic drugs, and so could increase the risk of low blood glucose(hypoglycemia).

There may be an increased risk of a drop in the normal numbers of white blood cells in the blood if Prinivil is taken in combination with any of the following medicines:
Allopurinol
Azathioprine
Immunosuppressant therapy
Procainamide

Pregnancy and Prinivil

Prinivil should not be used in pregnancy. Prinivil could cause birth defects in the baby if taken during pregnancy. If you get pregnant while taking Prinivil, talk to your physician right away. However, in some cases, where Prinivil is considered to be life-saving to the mother, treatment may be continued. It is not known if Prinivil passes into breast milk. Nursing mothers should switch to bottle-feed while using Prinivil.

Prinivil Doses

Prinivil should only be taken at doses directed by the physician.
Prinivil can be taken with or without food and at the same time each day.

Prinivil should not be taken within two hours of taking an antacid.

The dosage of Prinivil is lowered slowly when discontinuing.

The starting dose of Prinivil is 5 mg daily, and the effective dose range for treating heart failure is 5-40 mg daily. The dose can be increased by 10 mg every 2 weeks to achieve the maximum effect. The maximum dose is 40 mg daily.

The starting dose of Prinivil for treating hypertension is 10 mg daily. The usual dose range is 20-40 mg daily.
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